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KMID : 1098420050130040182
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Korean Journal of Medicinal Crop Science
2005 Volume.13 No. 4 p.182 ~ p.185
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Isolation of the Antimicrobial Compounds from Aralia cordata Thunb. Extract
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Han Wan-Soo
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Abstract
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Bioassay-guided isolation of the dried roots of Aralia continentalis led to the isolation of (-)-pimara-8(14), 15dien-19-oic acid (continentalic acid) and (24E)-Stigmasta-5,22-dien-3{beta}-ol (stagmasterol). Their structures were elucidated using ^1H-NMR, ^{13}C-NMR, UV and mass spectra analyses. The gram-positive bacterial, including methicilline-resistant (MRSA), were more sensitive to the continentalic acid and stagmasterol than gram-negative bacterial.
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KEYWORD
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Aralia continentalis, continentalic acid, stagmasterol, antibacterial activity
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